Protein domains in Prosite database.
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| Sigma-70 factors family signature 2 | [STN]-x(2)-[DENQ]-[LIVMT]-[GAS]-x(4)-[LIVMF]-[PSTG]-x(3)-[LIVMA]-x-[NQR]-[LIVMA]-[EQH]-x(3)-[LIVMFWK]-x(2)-[LIVM]. |
| Signal peptidases I lysine active site | K-R-[LIVMSTA](2)-[GA]-x-[PG]-G-[DEQ]-x-[LIVM]-x-[LIVMFY]. |
| Signal peptidases I serine active site | [GS]-{PR}-S-M-{RS}-[PS]-[AT]-[LF]. |
| Signal peptidases I signature 3 | [LIVMFYW](2)-{NLPA}-{T}-G-D-[NH]-{PIEW}-x(2)-[SND]-x(2)-[SG]. |
| Signal peptidases II signature | [LIVM]-x-[GASF]-[GA]-[GAST]-[LIVMTF]-[GAS]-N-[LVMFGIA]-[LIVFYGT]-D-[RIK]-[LIVMFAC]. |
| Site-specific recombinases active site | Y-[LIVAC]-R-[VA]-S-[ST]-x(2)-Q. |
| Site-specific recombinases signature 2 | G-[DE]-x(2)-[LIVM]-{E}-x-{V}-[LIVM]-[DT]-R-[LIVM]-[GSA]. |
| SLC26A transporters signature | [PAV]-x-[FYLCVI]-[GS]-L-Y-[STAG]-[STAGL]-x(4)-[LIVFYA]-[LIVMST]-[YI]-x(3)-[GA]-[GST]-[SRV]-[KRNP]. |
| Small cytokines (intercrine/chemokine) C-C subfamily signature | C-C-[LIFYTRQ]-x(5,8)-[LIR]-x(4)-[LIVMFA]-x(2)-[FYWECI]-x(5,8)-C-x(3,4)-[SAG]-[LIVM](2)-[FL]-x(7,9)-C-[STAV]. |
| Small cytokines (intercrine/chemokine) C-x-C subfamily signature | C-x-C-[LIVMS]-x(4,6)-[LIVMFY]-x(2)-[RKSEQNA]-x-[LIVM]-x(2)-[LIVMA]-x(5)-[STAG]-x(2)-C-x(3)-[EQ]-[LIVM](2)-x(9,10)-C-[LV]-[DN]. |
| Small hydrophilic plant seed proteins signature | G-[EQ]-T-V-V-P-G-G-T. |
| Small, acid-soluble spore proteins, alpha/beta type, signature 1 | K-x-E-[LIV]-A-x-[DE]-[LIVMF]-G-[LIVMF]. |
| Small, acid-soluble spore proteins, alpha/beta type, signature 2 | [KRC]-[SAQ]-x-G-x-[VF]-G-[GA]-x-[LIVM]-x-[KR]-[KRC]-[LIVM](2). |
| Snake toxins signature | G-C-x(1,3)-C-P-x(8,10)-C-C-x(2)-[PDEN]. |
| Sodium and potassium ATPases beta subunits signature 1 | [FYWMV]-x(2)-[FYWM]-x-[FYW]-[DN]-x(6)-[LIVMF]-[GA]-R-T-x(3)-[WRL]. |
| Sodium and potassium ATPases beta subunits signature 2 | [RK]-x(2)-C-[RKQWI]-x(5)-L-x(2)-C-[SA]-G. |
| Sodium:alanine symporter family signature | G-G-x-[GA](2)-[LIVM]-F-W-M-W-[LIVM]-x-[STAV]-[LIVMFA](2)-G. |
| Sodium:dicarboxylate symporter family signature 1 | P-x(0,1)-[GP]-[DES]-x-[LIVMF](2)-x-[LIVMA]-[LIVM]-[KREQS]-[LIVMG]-[LIVM]-[LIVMF]-x-[PS]. |
| Sodium:dicarboxylate symporter family signature 2 | P-x-G-x-[STA]-x-[NT]-[LIVMCP]-D-[GA]-[STANQF]-x-[LIVM]-[FY]-x(2)-[LIVM]-x(2)-[LIVM]-[FY]-[LIV]-[SA]-[QH]. |
| Sodium:galactoside symporter family signature | [DG]-x(3)-G-x(3)-[DN]-x(6,8)-[GA]-[KRHQ]-[FSAR]-[KRL]-[PT]-[FYW]-[LIVMWQ]-[LIV]-x(0,1)-[GAFV]-[GSTA]. |
| Sodium:neurotransmitter symporter family signature 1 | W-[RK]-F-[GPA]-[YF]-x(4)-[NYHS]-G-G-[GCA]-x-[FY]. |
| Sodium:neurotransmitter symporter family signature 2 | [YF]-[LIVMFY]-x(2)-[SC]-[LIVMFY]-[STQV]-x(2)-[LVI]-P-W-x(2)-C-x(3,4)-[NWDS]-[GSTERHAK]. |
| Sodium:solute symporter family signature 1 | [GS]-x(2)-[LIY]-x(3)-[LIVMFYWSTAG](7)-x(3)-[LIY]-[STAV]-x(2)-G-G-[LMF]-x-[SAP]. |
| Sodium:solute symporter family signature 2 | [GAST]-[LIVM]-x(3)-[KR]-x(4)-G-A-x(2)-[GAS]-[LIVMGS]-[LIVMW]-[LIVMGAT]-G-x-[LIVMGA]. |
| Sodium:sulfate symporter family signature | [STACPI]-S-x(2)-[FY]-x(2)-P-[LIVM]-[GSA]-x(3)-N-x-[LIVM]-V. |
| Somatomedin B domain (SMB) signature | C-x-C-x(3)-C-x(5,6)-C-C-x-[DN]-[FY]-x(3)-C. |
| Somatotropin, prolactin and related hormones signature 1 | C-x-[STN]-x(2)-[LIVMFYS]-x-[LIVMSTA]-P-x(5)-[TALIV]-x(7)-[LIVMFY]-x(6)-[LIVMFY]-x(2)-[STACV]-W. |
| Somatotropin, prolactin and related hormones signature 2 | C-[LIVMFY]-{PT}-x-D-[LIVMFYSTA]-x-{S}-{RK}-{A}-x-[LIVMFY]-x(2)-[LIVMFYT]-x(2)-C. |
| Soybean trypsin inhibitor (Kunitz) protease inhibitors family signature | [LIVM]-x-D-{EK}-[EDNTY]-[DG]-[RKHDENQ]-x-[LIVM]-x-{E}-{Q}-x(2)-Y-x-[LIVM]. |
| Spermadhesins family signature 1 | C-G-x(2)-[LIY]-x(4)-G-x-I-x(9)-C-x-W-T. |
| Spermadhesins family signature 2 | C-x-K-E-x-[LIVM]-E-[LIVM]-x-[DE]-x(3)-[GSE]-x(5)-K-x-C. |
| Spermidine/spermine synthases family signature | [VAI]-[LAV]-[LIV](2)-G-G-G-x-[GC]-x(2)-[LIVA]-x-E. |
| Spider toxin CSTX family signature | C-{C}(6)-C-{C}(6)-C-C-{C}(8)-C-{C}-C. |
| Squalene and phytoene synthases signature 1 | Y-[CSAM]-x(2)-[VSG]-A-[GSA]-[LIVAT]-[IV]-G-x(2)-[LMSC]-x(2)-[LIV]. |
| Squalene and phytoene synthases signature 2 | [LIVM]-G-x(3)-Q-x(2,3)-[ND]-[IFL]-x-[RE]-D-[LIVMFY]-x(2)-[DE]-x(4,7)-R-x-[FY]-x-P. |
| Squash family of serine protease inhibitors signature | C-P-x(5)-C-x(2)-[DN]-x-D-C-x(3)-C-x-C. |
| SRCR domain signature | [GNRVM]-x(5)-[GLKA]-x(2)-[EQ]-x(6)-[WPS]-[GLKH]-x(2)-C-x(3)-[FYW]-x(8)-[CM]-x(3)-G. |
| SRP54-type proteins GTP-binding domain signature | P-[LIVM]-x-[FYL]-[LIVMAT]-[GS]-{Q}-[GS]-[EQ]-x-{K}-x(2)-[LIVMF]. |
| SsrA-binding protein | [STAC]-G-[LIVM]-x-L-x-G-x-E-[LIVM]-[KQ]-[SA]-[LIVMA]. |
| Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2 | K-x(2)-[LIVF]-x(4)-[LIVF]-D-x(3)-R-x(2)-L-x(5)-[LIV]-Y. |
| Staphylocoagulase repeat signature | A-R-P-x(3)-K-x-S-x-T-N-A-Y-N-V-T-T-x(2)-[DN]-G-x(3)-Y-G. |
| Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1 | Y-G-G-[LIV]-T-{I}-{N}-x(2)-N. |
| Stathmin family signature 1 | P-[KRQ]-[KR](2)-[DE]-x-S-L-[EG]-E. |
| Stathmin family signature 2 | A-E-[KR]-R-E-H-E-[KR]-E-V. |
| Sterol reductase family signature 1 | G-x(2)-[LIVMF]-[IFYH]-[DN]-x-[FYWM]-x-G-x(2)-[LF]-[NY]-P-[RQ]. |
| Sterol reductase family signature 2 | [LIVM](2)-[LIVMFT]-[HWD]-R-x(2)-R-D-x(3)-C-x(2)-K-Y-[GK]-x(2)-[FW]-x(2)-Y. |
| Streptomyces subtilisin-type inhibitors signature | C-x-P-x(2,3)-G-x(0,1)-H-[PA]-x(4)-A-C-[ATDE]-x-L. |
| Stress-induced proteins SRP1/TIP1 family signature | P-W-Y-[ST](2)-R-L. |
| Succinate dehydrogenase cytochrome b subunit signature 1 | R-P-[LIVMT]-x(3)-[LIVM]-x(6)-[LIVMWPK]-x(4)-S-x(2)-H-R-x-[ST]. |
| Succinate dehydrogenase cytochrome b subunit signature 2 | H-x(3)-[GA]-[LIVMT]-R-[HF]-[LIVMF]-x-[FYWM]-D-x-[GVA]. |
| Sugar transport proteins signature 1 | [LIVMSTAG]-[LIVMFSAG]-{SH}-{RDE}-[LIVMSA]-[DE]-{TD}-[LIVMFYWA]-G-R-[RK]-x(4,6)-[GSTA]. |
| Sugar transport proteins signature 2 | [LIVMF]-x-G-[LIVMFA]-{V}-x-G-{KP}-x(7)-[LIFY]-x(2)-[EQ]-x(6)-[RK]. |
| Sulfatases signature 1 | [SAPG]-[LIVMST]-[CS]-[STACG]-P-[STA]-R-x(2)-[LIVMFW](2)-[TAR]-G. |
| Sulfatases signature 2 | G-[YV]-x-[ST]-x(2)-[IVAS]-G-K-x(0,1)-[FYWMK]-[HL]. |
| SURF4 family signature | [KR]-Y-[DE]-F-[FY]-Q-x(2)-S-x-[LIVM]-G-G-L-L. |
| Surfactant associated polypeptide SP-C palmitoylation sites | I-P-C-C-P-V. |
| Synapsins signature 1 | L-R-R-R-L-S-D-S. |
| Synapsins signature 2 | G-H-A-H-[SA]-G-M-G-K-[IV]-K. |
| Synaptobrevin signature | [NT]-[LIVMF]-[DENSTG]-[KLNRGS]-[VAI]-x-[DEQA]-R-x(2)-[KRN]-[LIVM]-[STDEA]-x-[LIVM]-x-[DEQGN]-[KR]-[TAS]-[DEAS]. |
| Synaptophysin / synaptoporin signature | L-S-V-[DE]-C-x-N-K-T. |
| Syndecans signature | [FY]-R-[IM]-[KR]-K(2)-D-E-G-S-Y. |
| Syntaxin / epimorphin family signature | [RQLKA]-x(3)-[LIVMAW]-x(2)-[LIVM]-[ESHLKAGQV]-x(2)-[LIVMT]-x-[DEVMNRAST]-[LIVMT]-x(2)-[LIVMQ]-[FSAQGVM]-x(2)-[LIVMF]-x(3)-[LIVT]-x(2)-Q-[GADEQVST]-x(2)-[LIVMA]-[DNQTEI]-x-[LIVMF]-[DESVHAG]-x(2,3)-[LIV. |
| T-box domain signature 1 | [LQI]-W-x(2)-[FCL]-x(3,4)-[NT]-E-[MQ]-[LIVNM]-[LIV]-[TLF]-x(2)-[GR]-[RG]-[KRQM]. |
| T-box domain signature 2 | [LIVMFYWE]-H-[PADHL]-[DENQRS]-[GSE]-x(3)-G-x(2)-[WL]-[ML]-x(3)-[IVA]-x-F. |
| Tachykinin family signature | F-[IVFY]-G-[LM]-M-[G>]. |
| TatC family signature | Y-x(2)-[FL]-[LIVMAFNT]-[LIVMAFT]-x-[LVSI]-x(4)-[GASF]-x(2)-F-[EQ]-[LIVMFC]-P-[LIVM]. |
| TatD deoxyribonuclease family signature 1 | [LIVMFY](2)-D-[STA]-H-x-H-[LIVMFP]-[DN]. |
| TatD deoxyribonuclease family signature 2 | P-[LIVM]-x-[LIVM]-H-x-R-x-[TA]-x-[DE]. |
| TatD deoxyribonuclease family signature 3 | [LVSAT]-[LIVA]-x(2)-[LIVMT]-[PSD]-x(3)-[LI]-[LIVMT]-[LIVMST]-E-T-D-x-P. |
| Tau and MAP proteins tubulin-binding domain signature | G-S-x(2)-N-x(2)-H-x-[PA]-[AG]-G(2). |
| TEA domain signature | G-R-N-E-L-I-x(2)-[YH]-I-x(3)-[TC]-x(3)-R-T-[RK](2)-Q-[LIVM]-S-S-H-[LIVM]-Q-V. |
| Terpene synthases signature | [DE]-G-S-W-x-[GE]-x-W-[GA]-[LIVM]-x-[FY]-x-Y-[GA]. |
| TetR-type HTH domain signature | [GS]-[LIVMFYSP]-x(2,3)-[TS]-[LIVMTA]-x(2)-[LIVM]-x(5)-[LIVQSA]-[STAGENQH]-x-[GPART]-x-[LIVMFA]-[FYSTNRH]-x-[HFYRA]-[FVW]-x-[DNSTKAG]-[KQMT]-x(2,3)-[LIVM]. |
| Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1 | [EQLT]-x-[EQKDS]-[LIVM](2)-x(2)-[LIVM]-x(2)-[LIVMY]-N-x-[DNS]-x(5)-[LIVMF](3)-Q-[LM]-P-[LVI]. |
| Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2 | P-[GK]-G-[VI]-G-P-[MFI]-T-[IVA]. |
| TGF-beta family signature | [LIVM]-x(2)-P-x(2)-[FY]-x(4)-C-x-G-x-C. |
| Thaumatin family signature | G-x-[GF]-x-C-x-T-[GA]-D-C-x(1,2)-[GQ]-x(2,3)-C. |
| Thermonuclease family signature 1 | D-G-D-T-[LIVM]-x-[LIVMC]-x(9,10)-R-[LIVM]-x(2)-[LIVM]-D-x-P-E. |
| Thermonuclease family signature 2 | [DT]-[KRP]-[YQ]-[GQ]-R-x-[LVY]-[GA]-x-[IV]-[FYW]. |
| Thiamine pyrophosphate enzymes signature | [LIVMF]-[GSA]-x(5)-P-x(4)-[LIVMFYW]-x-[LIVMF]-x-G-D-[GSA]-[GSAC]. |
| Thiol-activated cytolysins signature | [RK]-E-C-T-G-L-x-W-E-W-W-[RK]. |
| Thiolases active site | [AG]-[LIVMA]-[STAGCLIVM]-[STAG]-[LIVMA]-C-{Q}-[AG]-x-[AG]-x-[AG]-x-[SAG]. |
| Thiolases acyl-enzyme intermediate signature | [LIVM]-[NST]-{T}-x-C-[SAGLI]-[ST]-[SAG]-[LIVMFYNS]-x-[STAG]-[LIVM]-x(6)-[LIVM]. |
| Thiolases signature 2 | N-x(2)-G-G-x-[LIVM]-[SA]-x-G-H-P-x-[GAS]-x-[ST]-G. |
| Thioredoxin family active site | [LIVMF]-[LIVMSTA]-x-[LIVMFYC]-[FYWSTHE]-x(2)-[FYWGTN]-C-[GATPLVE]-[PHYWSTA]-C-{I}-x-{A}-x(3)-[LIVMFYWT]. |
| Thymidine and pyrimidine-nucleoside phosphorylases signature | [SA]-[GS]-R-[GA]-[LIV]-x(2)-[TAP]-[GAS]-G-T-x-D-x-[LIVMF]-[EDS]. |
| Thymidine kinase cellular-type signature | [GA]-x(1,2)-[DE]-x-Y-x-[STAPV]-x-C-[NKR]-x-[CH]-[LIVMFYWH]. |
| Thymidylate kinase signature | [LIV]-[LIVMGSTC]-[DET]-[RH]-[FYHCS]-x(2)-S-[GSTNP]-x-[AVC]-[FY]-[STANQ]. |
| Thymidylate synthase active site | R-x(2)-[LIVMT]-x(2,3)-[FWY]-[QNYDI]-x(8,13)-[LVESI]-x-P-C-[HAVMLC]-x(3)-[QMTLHD]-[FYWL]-x(0,1)-[LV]. |
| Thymosin beta-4 family signature | L-[KR]-K-T-[DENT]-T-x(2)-K-N-[PT]-L. |
| Thyroglobulin type-1 repeat signature | [FYWHPVAS]-x(3)-C-x(3,4)-[SG]-x-[FYW]-x(3)-Q-x(5,12)-[FYW]-C-[VA]-x(3,4)-[SG]. |
| Tissue factor signature | W-K-x-K-C-x(2)-T-x-[DEN]-T-E-C-D-[LIVM]-T-D-E. |
| Tissue inhibitors of metalloproteinases signature | C-x-C-x-P-x-H-P-Q-x(2)-[FIV]-C. |
| TNF family signature | [LV]-x-[LIVM]-{V}-x-{L}-G-[LIVMF]-Y-[LIVMFY](2)-x(2)-[QEKHL]-[LIVMGT]-x-[LIVMFY]. |
| TNFR/NGFR family cysteine-rich region signature | C-x(4,6)-[FYH]-x(5,10)-C-x(0,2)-C-x(2,3)-C-x(7,11)-C-x(4,6)-[DNEQSKP]-{PD}-{CP}-C. |
| TonB-dependent receptor proteins signature 1 | |
| TonB-dependent receptor proteins signature 2 | [LYGSTANEQ]-x(3)-[GSTAENQ]-x-[PGE]-R-x-[LIVFYWA]-x-[LIVMFTA]-[STAGNQ]-[LIVMFYGTA]-x-[LIVMFYWGTADQ]-x-F>. |
| Tpx family signature | S-x-D-L-P-F-[AS]-x(2)-[KRQ]-[FWI]-C. |
| Transaldolase active site | [LIVMA]-x-[LIVM]-K-[LIVM]-[PAS]-x-[STC]-x-[DENQPAS]-[GC]-[LIVM]-x-[AGV]-x(0,1)-[QEKRSTH]-x-[LIVMF]. |
| Transaldolase signature 1 | [DGH]-[IVSAC]-T-[ST]-N-P-[STA]-[LIVMF](2). |
