Protein domains in Prosite database.
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| Glutamate 5-kinase signature | [GSTNAD]-x(2)-[GAS]-x-G-[GC]-[IM]-x-[STAG]-K-[LIVMCT]-x-[SAI]-[TCAGFS]-x(2)-[GALVCMI]. |
| Glutamine synthetase class-I adenylation site | K-[LIVM]-x(5)-[LIVMA]-D-[RK]-[DN]-[LI]-Y. |
| Glutamine synthetase putative ATP-binding region signature | K-P-[LIVMFYA]-x(3,5)-[NPAT]-[GA]-[GSTAN]-[GA]-x-H-x(3)-S. |
| Glutamine synthetase signature 1 | [FYWL]-D-G-S-S-x(6,8)-[DENQSTAK]-[SA]-[DE]-x(2)-[LIVMFY]. |
| Glutamyl-tRNA reductase signature | [HY]-[LIVMAF]-x(2)-[LIVM]-[GSTACIV]-[GSTAC]-[GSA]-[LIVMFA]-[DEQHY]-S-x-[LIVMAS]-[LIVMFKS]-[GFA]-[DE]-x-[EQRD]-[IV]-[LIVTQAM]-[TAGRKS]-Q-[LIVMF]-[KRE]. |
| Glutamyl-tRNA(Gln) amidotransferase subunit B signature | [LMFYCVI]-[DN]-R-x(3)-[PGA]-L-[LIVMCA]-E-[LIVMT]-x-[STL]-x-[PA]. |
| Glutaredoxin active site | [LIVMD]-[FYSA]-x(4)-C-[PV]-[FYWH]-C-x(2)-[TAV]-x(2,3)-[LIV]. |
| Glutathione peroxidases active site | [GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-C-[GA]-x-[TA]. |
| Glutathione peroxidases signature 2 | [LIV]-[AGD]-F-P-[CS]-[NG]-Q-F. |
| Glyceraldehyde 3-phosphate dehydrogenase active site | [ASV]-S-C-[NT]-T-{S}-x-[LIM]. |
| Glycine radical domain signature | [STIV]-x-R-[IVT]-[CSA]-G-Y-{GI}-[GACV]. |
| Glycophorin A signature | I-I-x-[GAC]-V-M-A-G-[LIVM](2). |
| Glycoprotease family signature | [KRC]-[GSAT]-x(4)-[FYWLMH]-[DQNGKRH]-x-P-x-[LIVMFY]-x(3)-H-x(2)-[GSA]-H-[LIVMFA]. |
| Glycoprotein hormones alpha chain signature 1 | C-x-G-C-C-[FY]-S-[RQS]-A-[FY]-P-T-P. |
| Glycoprotein hormones alpha chain signature 2 | N-H-T-x-C-x-C-x-T-C-x(2)-H-K. |
| Glycoprotein hormones beta chain signature 1 | C-[STAGM]-G-[HFYL]-C-x-[ST]. |
| Glycoprotein hormones beta chain signature 2 | [PA]-V-A-x(2)-C-x-C-x(2)-C-x(4)-[STDAI]-[DEY]-C-x(6,8)-[PGSTAVMI]-x(2)-C. |
| Glycosyl hydrolases family 1 active site | [LIVMFSTC]-[LIVFYS]-[LIV]-[LIVMST]-E-N-G-[LIVMFAR]-[CSAGN]. |
| Glycosyl hydrolases family 1 N-terminal signature | F-x-[FYWM]-[GSTA]-x-[GSTA]-x-[GSTA](2)-[FYNH]-[NQ]-x-E-x-[GSTA]. |
| Glycosyl hydrolases family 10 active site | [GTA]-{QNAG}-{GSV}-[LIVN]-x-[IVMF]-[ST]-E-[LIY]-[DN]-[LIVMF]. |
| Glycosyl hydrolases family 11 active site signature 1 | [PSA]-[LQ]-x-E-[YF]-Y-[LIVM](2)-[DE]-x-[FYWHN]. |
| Glycosyl hydrolases family 11 active site signature 2 | [LIVMF]-x(2)-E-[AG]-[YWG]-[QRFGS]-[SG]-[STAN]-G-x-[SAF]. |
| Glycosyl hydrolases family 16 active sites | E-[LIV]-D-[LIVF]-x(0,1)-E-x(2)-[GQ]-[KRNF]-x-[PSTA]. |
| Glycosyl hydrolases family 17 signature | [LIVMKS]-x-[LIVMFYWA](3)-[STAG]-E-[STACVI]-G-[WY]-P-[STN]-x-[SAGQ]. |
| Glycosyl hydrolases family 2 acid/base catalyst | [DENQLF]-[KRVW]-N-[HRY]-[STAPV]-[SAC]-[LIVMFS]-[LIVMFSA]-[LIVMFS]-W-[GSV]-x(2,3)-N-E. |
| Glycosyl hydrolases family 2 signature 1 | N-x-[LIVMFYWD]-R-[STACN](2)-H-Y-P-x(4)-[LIVMFYWS](2)-x(3)-[DN]-x(2)-G-[LIVMFYW](4). |
| Glycosyl hydrolases family 25 active sites signature | D-[LIVM]-x(3)-[NQ]-[PGE]-x(9,15)-[GR]-x(4)-[LIVMFY](2)-K-x-[ST]-E-[GS]-x(2)-[FYL]-x-[DN]. |
| Glycosyl hydrolases family 3 active site | [LIVM](2)-[KR]-x-[EQKRD]-x(4)-G-[LIVMFTC]-[LIVT]-[LIVMF]-[ST]-D-x(2)-[SGADNIT]. |
| Glycosyl hydrolases family 31 active site | [GFY]-[LIVMF]-W-x-D-M-[NSA]-E. |
| Glycosyl hydrolases family 31 signature 2 | G-[AVP]-[DT]-[LIVMTAS]-[CG]-G-[FY]-x(3)-[STP]-x(3)-L-[CL]-x-R-W-x(2)-[LVMI]-[GSA]-[SA]-[FY]-x-P-[FY]-x-R-[DNA]. |
| Glycosyl hydrolases family 32 active site | H-x(2)-[PV]-x(4)-[LIVMA]-N-D-P-N-[GA]. |
| Glycosyl hydrolases family 35 putative active site | G-G-P-[LIVM](2)-x(2)-Q-x-E-N-E-[FY]. |
| Glycosyl hydrolases family 39 active site | W-x-F-E-x-W-N-E-P-[DN]. |
| Glycosyl hydrolases family 4 signature | [PS]-x-[SAC]-x-[LIVMFY](2)-[QN]-x(2)-N-P-x(4)-[TA]-x(9,11)-[KRD]-x-[LIV]-[GN]-x-C. |
| Glycosyl hydrolases family 45 active site | [STA]-T-R-Y-[FYW]-D-x(5)-[CA]. |
| Glycosyl hydrolases family 5 signature | [LIV]-[LIVMFYWGA](2)-[DNEQG]-[LIVMGST]-{SENR}-N-E-[PV]-[RHDNSTLIVFY]. |
| Glycosyl hydrolases family 6 signature 1 | V-x-Y-x(2)-P-x-R-D-C-[GSAF]-x(2)-[GSA](2)-x-G. |
| Glycosyl hydrolases family 6 signature 2 | [LIVMYA]-[LIVA]-[LIVT]-[LIV]-E-P-D-[SAL]-[LI]-[PSAG]. |
| Glycosyl hydrolases family 8 signature | A-[ST]-D-[AG]-D-x(2)-[IM]-A-x-[SA]-[LIVM]-[LIVMG]-x-A-x(3)-[FW]. |
| Glycosyl hydrolases family 9 active sites signature 1 | [STV]-x-[LIVMFY]-[STV]-x(2)-G-x-[NKR]-x(4)-[PLIVM]-H-x-R. |
| Glycosyl hydrolases family 9 active sites signature 2 | [FYW]-x-D-x(4)-[FYW]-x(3)-E-x-[STA]-x(3)-N-[STA]. |
| Glyoxalase I signature 1 | [HQ]-[IVT]-x-[LIVFY]-x-[IV]-x(4)-{E}-[STA]-x(2)-F-[YM]-x(2,3)-[LMF]-G-[LMF]. |
| Glyoxalase I signature 2 | G-[NTKQ]-x(0,5)-[GA]-[LVFY]-[GH]-H-[IVF]-[CGA]-x-[STAGLE]-x(2)-[DNC]. |
| Glypicans signature | C-x(2)-C-x-[GS]-[LIVM]-x(4)-P-C-x(2)-[FY]-C-x(2)-[LIVM]-x(2)-G-C. |
| GMC oxidoreductases signature 1 | [GA]-[RKNC]-x-[LIVW]-G(2)-[GST](2)-x-[LIVM]-[NH]-x(3)-[FYWA]-x(2)-[PAG]-x(5)-[DNESHQA]. |
| GMC oxidoreductases signature 2 | [GS]-[PSTA]-x(2)-[ST]-[PS]-x-[LIVM](2)-x(2)-S-G-[LIVM]-G. |
| Gonadotropin-releasing hormones signature | Q-[HY]-[FYW]-S-x(4)-P-G. |
| GPR1/FUN34/yaaH family signature | N-P-[AV]-P-[LF]-G-L-x-[GSA]-F. |
| Gram-negative pili assembly chaperone signature | [LIVMFY]-[APN]-x-[DNS]-[KREQ]-E-[STR]-[LIVMAR]-x-[FYWTE]-x-[NCS]-[LIVM]-x(2)-[LIVM]-P-[PAS]. |
| Granins signature 1 | [DE]-[SN]-L-[SAN]-{EGI}-{ELT}-[DE]-x-E-L. |
| Granins signature 2 | C-[LIVM](2)-E-[LIVM](2)-S-[DN]-[STA]-L-x-K-x-[SN]-x(3)-[LIVM]-[STA]-x-E-C. |
| Granulins signature | C-x-D-x(2)-H-C-C-P-x(4)-C. |
| Granulocyte-macrophage colony-stimulating factor signature | C-P-[LP]-T-x-E-[ST]-x-C. |
| grpE protein signature | [FYLV]-[DNST]-[PHEAYVS]-x(2)-[HMACNQ]-x-[ALV]-[LIVMTNSF]-x(16,21)-[GYP]-[FY]-x(3,4)-[DENGKS]-x(2,3)-[LIV]-[KRIV]-x-[STAG]-x-V-x(0,1)-[IV]. |
| GTP cyclohydrolase I signature 1 | [DENGQST]-[LIVMPF]-[LIVM]-x(1,2)-[KRNQELD]-[DENKGS]-[LIVM]-x(3)-[STG]-x-C-[EP]-H-H. |
| GTP cyclohydrolase I signature 2 | [SA]-x-[RK]-x-Q-[LIVMT]-Q-E-[RNAK]-[LIM]-[TSNV]. |
| GTP-binding elongation factors signature | D-[KRSTGANQFYW]-x(3)-E-[KRAQ]-x-[RKQD]-[GC]-[IVMK]-[ST]-[IV]-x(2)-[GSTACKRNQ]. |
| GTP-binding nuclear protein ran signature | D-T-A-G-Q-E-[KR]-[LFY]-G-G-L-R-[DE]-G-Y-[YF]. |
| GTP1/OBG family signature | D-[LIVMA]-P-G-[LIVM](2)-[DEYPKQV]-[GN]-A-x(2)-G-x-G. |
| Guanylate cyclase signature | [GD]-[VI]-[LIVM]-x(0,1)-[GS]-x(5)-[FY]-x-[LIVM]-[FYWL]-[GS]-[DNTHKWE]-[DNTAS]-[IV]-[DNTAY]-x(5)-[DEC]. |
| Guanylate kinase-like signature | [TS]-[ST]-R-x(2)-[KR]-x(2)-[DE]-x(2)-[GA]-x(2)-Y-x-[FY]-[LIVMKHRT]. |
| HBGF/FGF family signature | G-x-[LIM]-x-[STAGP]-x(6,7)-[DENA]-C-x-[FLM]-x-[EQ]-x(6)-Y. |
| HCP repeats signature | H-R-H-R-G-H-x(2)-[DE](7). |
| Heat shock hsp70 proteins family signature 1 | [IV]-D-L-G-T-[ST]-x-[SC]. |
| Heat shock hsp70 proteins family signature 2 | [LIVMF]-[LIVMFY]-[DN]-[LIVMFS]-G-[GSH]-[GS]-[AST]-x(3)-[ST]-[LIVM]-[LIVMFC]. |
| Heat shock hsp70 proteins family signature 3 | [LIVMY]-x-[LIVMF]-x-G-G-x-[ST]-{LS}-[LIVM]-P-x-[LIVM]-x-[DEQKRSTA]. |
| Heat shock hsp90 proteins family signature | Y-x-[NQHD]-[KHR]-[DE]-[IVA]-F-[LM]-R-[ED]. |
| Heat-stable enterotoxins signature | C-C-x(2)-C-C-x-P-A-C-x-G-C. |
| Heavy-metal-associated domain | [LIVNS]-x-{L}-[LIVMFA]-x-C-x-[STAGCDNH]-C-x(3)-[LIVFG]-{LV}-x(2)-[LIV]-x(9,11)-[IVA]-x-[LVFYS]. |
| Heme oxygenase signature | L-[IV]-A-H-[STACH]-Y-[STV]-[RT]-Y-[LIVM]-G. |
| Heme-copper oxidase catalytic subunit, copper B binding region signature | [YWG]-[LIVFYWTA](2)-[VGS]-H-[LNP]-x-V-x(44,47)-H-H. |
| Hemerythrin family signature | H-F-x(2)-[EQ]-[ENQ]-x(2)-[LMF]-x(4,7)-[FY]-x(5,6)-H-x(3)-[HR]. |
| Hemolysin-type calcium-binding region signature | D-x-[LI]-x(4)-G-x-D-x-[LI]-x-G-G-x(3)-D. |
| Hemopexin domain signature | [LIFAT]-{IL}-x(2)-W-x(2,3)-[PE]-x-{VF}-[LIVMFY]-[DENQS]-[STA]-[AV]-[LIVMFY]. |
| Hexapeptide-repeat containing-transferases signature | [LIV]-[GAED]-x(2)-[STAV]-x-[LIV]-x(3)-[LIVAC]-x-[LIV]-[GAED]-x(2)-[STAVR]-x-[LIV]-[GAED]-x(2)-[STAV]-x-[LIV]-x(3)-[LIV]. |
| Hexokinases signature | [LIVM]-G-F-[TN]-F-S-[FY]-P-x(5)-[LIVM]-[DNST]-x(3)-[LIVM]-x(2)-W-T-K-x-[LF]. |
| High potential iron-sulfur proteins signature | C-x(6,9)-[LIVM]-x(3)-G-[YW]-C-x(2)-[FYW]. |
| Histidine acid phosphatases active site signature | [LIVMF]-x-[LIVMFAG]-{T}-x-[STAGI]-H-D-[STANQ]-{V}-[LIVM]-x(2)-[LIVMFY]-x(2)-[STA]. |
| Histidine acid phosphatases phosphohistidine signature | [LIVM]-x(2)-[LIVMA]-x(2)-[LIVM]-x-R-H-[GN]-x-R-x-[PAS]. |
| Histidinol dehydrogenase signature | [IVTPM]-[DEG]-x(2,3)-[AYEPQ]-G-[PT]-[ST]-[ED]-[LIVSTA]-[LIVMAECGFT]-[LIVMA]-[LIVMAYF]-[ACNDSTI]-x(2,3)-[ACNGVST]-x(4,6)-[LIVMAC]-[AVLKIT]-[SACLYWNRMTV]-[DEG]-[LIVMFCA]-[LIVMKFR]-[SAGVI]-x(2)-E-H. |
| Histone H2A signature | [AC]-G-L-x-F-P-V. |
| Histone H2B signature | [KR]-E-[LIVM]-[EQ]-T-x(2)-[KR]-x-[LIVM](2)-x-[PAG]-[DE]-L-x-[KR]-H-A-[LIVM]-[STA]-E-G. |
| Histone H3 signature 1 | K-A-P-R-K-[QH]-[LI]. |
| Histone H3 signature 2 | P-F-x-[RA]-L-[VA]-[KRQ]-[DEG]-[IV]. |
| Histone H4 signature | G-A-K-R-H. |
| HIT domain signature | [NQAR]-x(4)-[GSAVY]-x-[QFLPA]-x-[LIVMY]-x-[HWYRQ]-[LIVMFYST]-H-[LIVMFT]-H-[LIVMF]-[LIVMFPT]-[PSGAWN]. |
| HlyD family secretion proteins signature | [LIVM]-x(2)-G-[LM]-x(3)-[STGAV]-x-[LIVMT]-x-[LIVMTK]-[GE]-x-[KR]-x-[LIVMFYW](2)-x-[LIVMFYW](2)-[LIVMFYWK]. |
| HMG box A DNA-binding domain signature | [FI]-S-[KR]-K-C-x-[EK]-R-W-K-T-[MV]. |
| HMG-I and HMG-Y DNA-binding domain (A+T-hook) | [AT]-x(1,2)-[RK](2)-[GP]-R-G-R-P-[RK]-x. |
| HMG14 and HMG17 signature | [RQ]-R-S-A-[RS]-L-S-A-[RKM]-[PL]. |
| Hok/gef family cell toxic proteins signature | [LIVMA](4)-C-[LIVMFA]-T-[LIVMA](2)-x(4)-[LIVM]-x-[RG]-x(2)-L-[CY]. |
| Homoserine dehydrogenase signature | A-x(3)-G-[LIVMFY]-[STAG]-x(2,3)-[DNS]-P-x(2)-D-[LIVM]-x-G-x-D-x(3)-K. |
| HSF-type DNA-binding domain signature | L-x(3)-[FY]-K-H-x-N-x-[STAN]-S-F-[LIVM]-R-Q-L-[NH]-x-Y-x-[FYW]-[RKH]-K-[LIVM]. |
| Huwentoxin-1 family signature | C-[KALRVG]-x-{M}-x(1,3)-C-x(4,6)-C-C-x(4,6)-C-x(4)-[ERK]-W-C. |
| Huwentoxin-2 family signature | C-x(1,4)-[FLIV]-[SEP]-C-[DE]-[EIQ]-x(4,7)-C-x(0,7)-C-[KST]-x(4,18)-C-[YK]-x(1,3)-C. |
| Hydrogenases expression/synthesis hupF/hypC family signature | |
| Hydrogenases expression/synthesis hypA family signature | [GS]-x(4)-[LIVMT]-x(4)-[LIVMF]-x(2)-[CSAM]-[LMFY]-x(6)-[STC]-x(4,5)-[PAC]-x-[LIVMF]-x-[LIVMF]-x(8)-C-x(1,2)-[CH]. |
| Hydroxymethylglutaryl-coenzyme A lyase active site | S-V-A-G-L-G-G-C-P-Y. |
| Hydroxymethylglutaryl-coenzyme A reductases signature 1 | [RKH]-x-{Y}-{I}-x-{I}-{L}-D-x-M-G-x-N-x-[LIVMA]. |
| Hydroxymethylglutaryl-coenzyme A reductases signature 2 | [LIVM]-G-x-[LIVM]-G-G-[AG]-T. |
