Protein domains in Prosite database.
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| Transcription factor TFIIB repeat signature | G-[KR]-x(3)-[STAGN]-{S}-[LIVMYA]-[GSTA](2)-[CSAV]-[LIVM]-[LIVMFY]-[LIVMA]-[GSA]-[STAC]. |
| Transcription factor TFIID repeat signature | Y-x-[PK]-x(2)-[IF]-x(2)-[LIVM](2)-x-[KRH]-x(3)-P-[RKQ]-x(3)-L-[LIVM]-F-x-[STN]-G-[KR]-[LIVMA]-x(3)-G-[TAGL]-[KR]-x(7)-[AGCS]-x(7)-[LIVMF]. |
| Transcription termination factor nusG signature | [LIVM]-F-G-[KRW]-x-T-P-[IV]-x-[LIVM]. |
| Transcriptional antiterminators bglG family signature | [ST]-[DM]-H-[LIC]-x(2)-[FA]-[LIY]-[EQK]-R-x(2)-[QNKA]. |
| Transferrins signature 1 | Y-x(0,1)-[VAS]-V-[IVAC]-[IVA]-[IVA]-[RKH]-[RKS]-[GDENSA]. |
| Transferrins signature 2 | [YI]-x-G-A-[FLI]-[KRHNQS]-C-L-x(3,4)-G-[DENQ]-V-[GAT]-[FYW]. |
| Transferrins signature 3 | [DENQK]-[YF]-x-[LY]-L-C-x-[DN]-x(5,8)-[LIV]-x(4,5)-C-x(2)-A-x(4)-[HQR]-x-[LIVMFYW]-[LIVM]. |
| Transglutaminases active site | [GT]-Q-[CA]-W-V-x-[SA]-[GAS]-[IVT]-x(2)-T-x-[LMSC]-R-[CSAG]-[LV]-G. |
| Transketolase signature 1 | R-x(3)-[LIVMTA]-[DENQSTHKF]-x(5,6)-[GSN]-G-H-[PLIVMF]-[GSTA]-x(2)-[LIMC]-[GS]. |
| Transketolase signature 2 | [GP]-[DEQGSANPHVT]-[DN]-G-[PAEQ]-[ST]-[HQ]-x-[PAGM]-[LIVMYACNQS]-[DEFYWLA]-x(2)-[STAPG]-x(2)-[RGANQS]. |
| Translationally controlled tumor protein signature 1 | [IFAED]-[GA]-[GASF]-N-[PAK]-S-[GTA]-E-[GDEVCF]-[PAGEQV]-[DEQGAV]. |
| Translationally controlled tumor protein signature 2 | [FLIV]-x(4)-[FLVH]-[FY]-[MIVCT]-G-E-x(4,7)-[DENP]-[GAST]-x-[LIVM]-[GAVI]-x(3)-[FYWQ]. |
| Transmembrane 4 family signature | [GC]-x(3)-[LIVMFS]-x(2)-[GSA]-[LIVMFTC]-[LIVMFA]-G-[CLYI]-x-[GA]-[STAPL]-x(2)-[EGAR]-x(2)-[CWNLF]-[LIVMGA]-[LIVM]. |
| Transposases, IS30 family, signature | R-G-x(2)-E-N-x-N-G-[LIVM](2)-R-[QE]-[LIVMFY](2)-P-K. |
| Transposases, Mutator family, signature | D-x(3)-G-[LIVMF]-x(6)-[STAV]-[LIVMFYW]-[PT]-x-[STAV]-x(2)-[QR]-x-C-x(2)-H. |
| Transthyretin signature 1 | [KH]-[IV]-L-[DN]-x(3)-G-x-P-[AG]-x(2)-[LIVM]-x-[IV]. |
| Transthyretin signature 2 | [YWF]-[TH]-[IVT]-[AP]-x(2)-[LIVM]-[STA]-[PQ]-[FYWG]-[GS]-[FY]-[QST]. |
| Trehalase signature 1 | P-G-G-R-F-x-E-x-Y-x-W-D-x-Y. |
| Trehalase signature 2 | Q-W-D-x-P-x-[GAV]-W-[PAS]-P. |
| Triosephosphate isomerase active site | [AVG]-[YLV]-E-P-[LIVMEPKST]-[WYEAS]-[SAL]-[IV]-[GN]-[TEKDVS]-[GKNAD]. |
| Tropomyosins signature | L-K-[EAD]-A-E-x-R-A-[ET]. |
| Trp-Asp (WD) repeats signature | [LIVMSTAC]-[LIVMFYWSTAGC]-[LIMSTAG]-[LIVMSTAGC]-x(2)-[DN]-x-{P}-[LIVMWSTAC]-{DP}-[LIVMFSTAG]-W-[DEN]-[LIVMFSTAGCN]. |
| Tryptophan pentad repeat (IRF family) signature | W-x-[DNH]-x(5)-[LIVF]-x-[IV]-P-W-x-H-x(9,10)-[DE]-x(2)-[LIVF]-F-[KRQ]-x-[WR]-A. |
| Tryptophan synthase alpha chain signature | [LIVM]-E-[LIVM]-[GQ]-x(2)-[FYCHTWP]-[STPK]-[DEKY]-[PA]-[LIVMYGK]-[SGALIMY]-[DE]-[GN]. |
| Tryptophan synthase beta chain pyridoxal-phosphate attachment site | [LIVMYAHQ]-x-[HPYNVF]-x-G-[STA]-H-K-x-N-x(2)-[LIVM]-x-[QEH]. |
| TSC-22 / dip / bun family signature | M-D-L-V-K-x-H-L-x(2)-A-V-R-E-E-V-E. |
| Tub family signature 1 | F-[KRHQ]-G-R-V-[ST]-x-A-S-V-K-N-F-Q. |
| Tub family signature 2 | A-F-[AG]-I-[GSAC]-[LIVM]-[ST]-S-F-x-[GST]-K-x-A-C-E. |
| Tubulin subunits alpha, beta, and gamma signature | [SAG]-G-G-T-G-[SA]-G. |
| Tubulin-beta mRNA autoregulation signal | |
| Type-1 copper (blue) proteins signature | [GA]-x(0,2)-[YSA]-x(0,1)-[VFY]-{SEDT}-C-x(1,2)-[PG]-x(0,1)-H-x(2,4)-[MQ]. |
| Tyrosinase and hemocyanins CuB-binding region signature | D-P-x-F-[LIVMFYW]-x(2)-H-x(3)-D. |
| Tyrosinase CuA-binding region signature | H-x(4,5)-F-[LIVMFTP]-x-[FW]-H-R-x(2)-[LVMT]-x(3)-E. |
| Tyrosine kinase phosphorylation site | [RK]-x(2,3)-[DE]-x(2,3)-Y. |
| Tyrosine protein kinases specific active-site signature | [LIVMFYC]-{A}-[HY]-x-D-[LIVMFY]-[RSTAC]-{D}-{PF}-N-[LIVMFYC](3). |
| Tyrosine specific protein phosphatases active site | [LIVMF]-H-C-x(2)-G-x(3)-[STC]-[STAGP]-x-[LIVMFY]. |
| UbiA prenyltransferase family signature | N-x(3)-[DEH]-x(2)-[LIMFYT]-D-x(2)-[VM]-x-R-[ST]-x(2)-R-x(4)-[GYNKR]. |
| ubiE/COQ5 methyltransferase family signature 1 | Y-[DN]-x-[MLAFTI]-N-x(2)-[LIVMN]-S-x(3)-[HQD]-x(2)-W. |
| ubiE/COQ5 methyltransferase family signature 2 | R-V-[LIVMCT]-[KRQ]-[PVRK]-[GMKD]-[GAS]-x-[LIVMFAT]-x(2)-[LIVMCA]-[ED]-x-[SGT]. |
| ubiH/COQ6 monooxygenase family signature | H-P-[LIV]-[AG]-G-Q-G-x-N-x-G-x(2)-D. |
| Ubiquitin carboxyl-terminal hydrolase family 1 cysteine active-site | Q-x(3)-N-[SA]-C-G-x(3)-[LIVM](2)-H-[SA]-[LIVM]-[SA]. |
| Ubiquitin carboxyl-terminal hydrolases family 2 signature 1 | G-[LIVMFY]-x(1,3)-[AGCY]-[NASMQG]-x-C-[FYWC]-[LIVMFCA]-[NSTAD]-[SACV]-x-[LIVMSF]-[QF]. |
| Ubiquitin carboxyl-terminal hydrolases family 2 signature 2 | [YMF]-x-[LK]-x-[SAGNC]-[LIVMFT]-x(2)-H-x-G-x(4,6)-G-H-[YF]. |
| Ubiquitin domain signature | K-x(2)-[LIVM]-x-[DESAK]-x(3)-[LIVM]-[PAQ]-x(3)-Q-x-[LIVM]-[LIVMC]-[LIVMFY]-x-G-x(4)-[DE]. |
| Ubiquitin-activating enzyme active site | P-[LIVMG]-C-T-[LIVM]-[KRHA]-x-[FTNM]-P. |
| Ubiquitin-activating enzyme signature 1 | K-[AI]-[CL]-S-G-K-[FI]-x-[PQ]. |
| Ubiquitin-conjugating enzymes active site | [FYWLSP]-H-[PC]-[NHL]-[LIV]-x(3,4)-G-x-[LIVP]-C-[LIV]-x(1,2)-[LIVR]. |
| UDP-glycosyltransferases signature | [FW]-x(2)-[QL]-x(2)-[LIVMYA]-[LIMV]-x(4,6)-[LVGAC]-[LVFYAHM]-[LIVMF]-[STAGCM]-[HNQ]-[STAGC]-G-x(2)-[STAG]-x(3)-[STAGL]-[LIVMFA]-x(4,5)-[PQR]-[LIVMTA]-x(3)-[PA]-x(2,3)-[DES]-[QEHNR]. |
| Uncharacterized protein family UPF0001 signature | [FW]-H-[FM]-[IV]-G-x-[LIV]-Q-x-[NKRQ]-[KN]-x(3)-[LIV]. |
| Uncharacterized protein family UPF0003 signature | G-[STIF]-V-x(2)-[LIVM]-x(6)-[LIVMF]-x(3)-[DQT]-x(3)-[LIVH]-x-[LIV]-P-[NW]-x(2)-[LIVMF]-[LIVFSTA]-x(5)-[NV]. |
| Uncharacterized protein family UPF0004 signature | [LIVM]-x-[LIVMT]-x(2)-G-C-x(3)-C-[STAN]-[FY]-C-x-[LIVMT]-x(4)-G. |
| Uncharacterized protein family UPF0011 signature | S-[DN]-[AS]-G-x-P-x-[LIV]-[SNC]-D-P-G. |
| Uncharacterized protein family UPF0012 signature | [GTAL]-x(2)-[IVT]-C-Y-D-[LIVM]-x-F-P-x(9)-[GD]. |
| Uncharacterized protein family UPF0016 signature | E-[LIVM]-G-D-K-T-F-[LIVMF](2)-A. |
| Uncharacterized protein family UPF0017 signature | D-x(8)-[GN]-[LFY]-x(4)-[DET]-[LY]-Y-x(3)-[ST]-x(7)-[IV]-x(2)-[PS]-x-[LIVM]-x-[LIVM]-x(3)-[DN]-D. |
| Uncharacterized protein family UPF0020 signature | D-P-[LIVMF]-C-G-[ST]-G-x(3)-[LI]-E. |
| Uncharacterized protein family UPF0021 signature | C-K-x(2)-F-x(4)-E-x(22,23)-S-G-G-K-D. |
| Uncharacterized protein family UPF0023 signature | [DEN]-x(2)-[LIVF]-[DE](2)-[LIV]-L-x(4)-[IV]-[FY]-x(4)-K-G. |
| Uncharacterized protein family UPF0024 signature | G-x-K-D-[KRAT]-x-[AG]-[LVRSIT]-[TKS]-x-Q-x-[LIVF]-[SGCYAT]. |
| Uncharacterized protein family UPF0025 signature | D-V-[LIV]-x(2)-G-H-[ST]-H-x(12)-[LIVMF]-N-P-G. |
| Uncharacterized protein family UPF0027 signature | Q-[LIVM]-x-N-x-A-x-[LIVM]-P-x-I-x(6)-[LIVM]-P-D-x-H-x-G-x-G-x(2)-[IV]-G. |
| Uncharacterized protein family UPF0028 signature | [GA]-[GS]-G-[GA]-A-R-G-x-[SA]-H-x-G-x(9)-[IVY]-x-[IV]-[DV]-x(2)-[GA]-G-x-S-x-G. |
| Uncharacterized protein family UPF0029 signature | G-x(2)-[LIVM](2)-x(2)-[LIVM]-x(4)-[LIVM]-x(5)-[LIVM](2)-x-R-[FYW](2)-G-G-x(2)-[LIVM]-G. |
| Uncharacterized protein family UPF0031 signature 1 | [SAV]-[IVW]-[LVA]-[LIV]-G-[PNS]-G-L-[GP]-x-[DENQT]. |
| Uncharacterized protein family UPF0031 signature 2 | [GA]-G-x-G-D-[TV]-[LT]-[STA]-G-x-[LIVM]. |
| Uncharacterized protein family UPF0033 signature | [LIV]-[DEN]-x(2)-[TAG]-x(2)-C-P-x-[PT]-x-[LIVMF]-x(11)-[GN]. |
| Uncharacterized protein family UPF0034 signature | [LIVM]-[DNG]-[LIVMF]-N-x-G-C-[PS]-x(3,4)-[LIVMASQ]-x(5,6)-G-[SACY]. |
| Uncharacterized protein family UPF0035 signature | [LM]-[LF]-T-x-R-[SA]-x(3)-[RK]-x(3)-G-x(3)-F-P-G-G. |
| Uncharacterized protein family UPF0036 signature | H-x-S-G-H-[GA]-x(3)-[DE]-x(3)-[LM]-x(5)-P-x(3)-[LIVM]-P-x-H-G-[DE]. |
| Uncharacterized protein family UPF0047 signature | S-x(2)-[LIV]-x-[LIV]-x(2)-G-x(4)-G-T-W-Q-x-[LIV]. |
| Uncharacterized protein family UPF0054 signature | H-[GSA]-x-[LVCYT]-H-[LAI]-[LIMSANQVF]-G-[FYWMH]-x-[HD]. |
| Uncharacterized protein family UPF0057 signature | [LIVF]-x-[STAC]-[LIVF](3)-P-[PF]-[LIVA]-[GAV]-[IV]-x(4)-[GKN]. |
| Uncharacterized protein family UPF0066 signature | G-[AV]-F-[STA]-x-R-[SA]-x(2)-R-P-N. |
| Uncharacterized protein family UPF0067 signature | D-V-x(5)-H-I-[SA]-C-D-x(4)-S-E. |
| Uncharacterized protein family UPF0076 signature | [PA]-[ASTPV]-R-[SACVF]-x-[LIVMFY]-x(2)-[GSAKR]-x-[LMVA]-x(5,8)-[LIVM]-E-[MI]. |
| Undecaprenyl pyrophosphate synthetase family signature | [DEH]-[LIVMF]-[LIVMFC]-[LIVMF]-R-[STPV]-[SGAC]-[GEN]-x(1,2)-R-x-S-x-[FY]-[LMFV]-[LIPMVT]-[YWL]. |
| Uracil-DNA glycosylase signature | [KR]-[LIVA]-[LIVC]-[LIVM]-x-G-[QI]-D-P-Y. |
| Urease active site | [LIVM](2)-[CT]-H-[HNG]-L-x(3)-[LIVM]-x(2)-D-[LIVM]-x-F-[AS]. |
| Urease nickel ligands signature | T-[AY]-[GA]-[GATR]-[LIVMF]-D-x-H-[LIVM]-H-x(3)-[PA]. |
| Uricase signature | [LV]-x-[LV]-[LIV]-K-[STV]-[ST]-x-[SN]-x-F-x(2)-[FY]-x(4)-[FY]-x(2)-L-x(5)-R. |
| Urocanase signature | R-D-H-x-D-x-[GS]-[GS]-x(2)-S-P-x-R-E-T. |
| Uroporphyrin-III C-methyltransferase signature 1 | [LIVM]-[GS]-[STAL]-G-P-G-x(3)-[LIVMFY]-[LIVM]-T-[LIVM]-[KRHQG]-[AG]. |
| Uroporphyrin-III C-methyltransferase signature 2 | [VW]-x(2)-[LI]-x(2)-[GA]-[DT]-x(3)-[FYW]-[GS]-x(8)-[LIVFA]-x(5,6)-[LIVMFYWPAC]-x-[LIVMY]-x-[PN]-G. |
| Uroporphyrinogen decarboxylase signature 1 | [SP]-[IVCLAM]-W-[LIVMFYC]-[LM]-R-[QR]-[AVS]-G-R. |
| Uroporphyrinogen decarboxylase signature 2 | [LIMF]-[GAVS]-F-[STAGCV]-[STAGC]-x-[PA]-[FWYV]-T-[LIVM]-x(2)-Y-x(2,3)-[ADE]-[GK]. |
| Urotensin II signature | C-F-W-K-Y-C. |
| Vertebrate metallothioneins signature | C-x-C-[GSTAP]-x(2)-C-x-C-x(2)-C-x-C-x(2)-C-x-K. |
| Vinculin family talin-binding region signature | [KR]-x-[LIVMF]-x(3)-[LIVMA]-x(2)-[LIVM]-x(6)-R-Q-Q-E-L. |
| Vinculin repeated domain signature | [LIVM]-x-[QA]-A-x(2)-W-[IL]-x-[DN]-P. |
| Visual pigments (opsins) retinal binding site | [LIVMFWAC]-[PSGAC]-x-{G}-x-[SAC]-K-[STALIMR]-[GSACPNV]-[STACP]-x(2)-[DENF]-[AP]-x(2)-[IY]. |
| Vitamin K-dependent carboxylation domain | E-x(2)-[ERK]-E-x-C-x(6)-[EDR]-x(10,11)-[FYA]-[YW]. |
| VWFC domain signature | C-x(2,3)-C-{CG}-C-x(6,14)-C-x(3,4)-C-x(2,10)-C-x(9,16)-C-C-x(2,4)-C. |
| WAP-type 'four-disulfide core' domain signature | C-{G}-{C}-[DN]-x(2)-C-x(3)-{G}-x-C-C. |
| WHEP-TRS domain signature | [QYR]-[GH]-[DNEAR]-x-[LIV]-[KR]-x(2)-K-x(2)-[KRNG]-[AS]-x(4)-[LIV]-[DENKA]-x(2)-[IV]-x(2)-L-x(3)-K. |
| Wnt-1 family signature | C-[KR]-C-H-G-[LIVMT]-S-G-x-C. |
| WW/rsp5/WWP domain signature | W-x(9,11)-[VFY]-[FYW]-x(6,7)-[GSTNE]-[GSTQCR]-[FYW]-{R}-{SA}-P. |
| Xanthine/uracil permeases family signature | [LIVM]-P-x-[PASIF]-V-[LIVMG]-[GF]-[GA]-x(4)-[LIVM]-[FY]-[GSA]-x-[LIVM]-x(3)-[GA]. |
| XPA protein signature 1 | C-x-[DE]-C-x(3)-[LIVMF]-x(1,2)-D-x(2)-L-x(3)-F-x(4)-C-x(2)-C. |
| XPA protein signature 2 | [LIVM](2)-T-[KR]-T-E-x-K-x-[DE]-Y-[LIVMF](2)-x-D-x-[DE]. |
| XPG protein signature 1 | [VILT]-[KREIT]-[PV]-x-[FYIL]-[VI]-[FW]-D-G-x(2)-[PILHSTF]-x-[LVCQMFAKS]-K. |
