Protein domains in Prosite database.
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| C-5 cytosine-specific DNA methylases C-terminal signature | [RKQGTF]-x(2)-G-N-[SA]-[LIVF]-x-[VIP]-x-[LVMT]-x(3)-[LIVM]-x(3)-[LIVM]. |
| C-terminal cystine knot signature | C-C-x(13)-C-x(2)-[GN]-x(12)-C-x-C-x(2,4)-C. |
| C-type lectin domain signature | C-[LIVMFYATG]-x(5,12)-[WL]-{T}-[DNSR]-{C}-{LI}-C-x(5,6)-[FYWLIVSTA]-[LIVMSTA]-C. |
| Cadherin domain signature | [LIV]-x-[LIV]-x-D-x-N-D-[NH]-x-P. |
| Calcitonin / CGRP / IAPP family signature | C-[SAGDN]-[STN]-x(0,1)-[SA]-T-C-[VMA]-x(3)-[LYF]-x(3)-[LYF]. |
| Calcium-binding EGF-like domain signature | [DEQN]-x-[DEQN](2)-C-x(3,14)-C-x(3,7)-C-x-[DN]-x(4)-[FY]-x-C. |
| Calponin-like repeat signature | [LIVM]-x-[LS]-Q-[MASY]-G-[STY]-[NT]-[KRQ]-x(2)-[STN]-Q-x-G-x(3,4)-G. |
| Calreticulin family repeated motif signature | [IVM]-x-[DV]-x-[DENST]-x(2)-K-P-[DEH]-D-W-[DEN]. |
| Calreticulin family signature 1 | [KRHN]-x-[DEQN]-[DEQNK]-x(3)-C-G-G-[AG]-[FY]-[LIVM]-[KN]-[LIVMFY](2). |
| Calreticulin family signature 2 | [LIVM](2)-F-G-P-D-x-C-[AG]. |
| Calsequestrin signature 1 | [EQ]-[DE]-G-L-[DN]-F-P-x-Y-D-G-x-D-R-V. |
| Calsequestrin signature 2 | [DE]-L-E-D-W-[LIVM]-E-D-V-L-x-G-x-[LIVM]-N-T-E-D-D-D. |
| cAMP phosphodiesterases class-II signature | H-x-H-L-D-H-[LIVM]-x-[GS]-[LIVMA]-[LIVM](2)-x-S-[AP]. |
| cAMP- and cGMP-dependent protein kinase phosphorylation site | [RK](2)-x-[ST]. |
| CAP protein signature 1 | [LIVM](2)-x-R-L-[DE]-x(4)-R-L-E. |
| CAP protein signature 2 | D-[LIVMFY]-x-E-x-[PA]-x-P-E-Q-[LIVMFY]-K. |
| CAP-Gly domain signature | [GD]-x(0,10)-[FYWA]-x(0,1)-G-[LIVM]-x(0,2)-[LIVMFYD]-x(0,7)-G-[KN]-[NHW]-x(0,1)-G-[STARCV]-x(0,2)-[GD]-x(0,2)-[LY]-[FC]. |
| Carbamoyl-phosphate synthase subdomain signature 1 | [FYV]-[PS]-[LIVMC]-[LIVMA]-[LIVM]-[KR]-[PSA]-[STA]-x(3)-[SG]-G-x-[AG]. |
| Carbamoyl-phosphate synthase subdomain signature 2 | [LIVMF]-[LIMN]-E-[LIVMCA]-N-[PATLIVM]-[KR]-[LIVMSTAC]. |
| Carboxylesterases type-B serine active site | F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G. |
| Carboxylesterases type-B signature 2 | [EDA]-[DG]-C-L-[YTF]-[LIVT]-[DNS]-[LIV]-[LIVFYW]-x-[PQR]. |
| Casein kinase II phosphorylation site | [ST]-x(2)-[DE]. |
| Casein kinase II regulatory subunit signature | C-P-x-[LIVMYAT]-x-C-x(5)-[LI]-P-[LIVMCA]-G-x(9)-V-[KRM]-x(2)-C-[PA]-x-C. |
| Caseins alpha/beta signature | C-L-[LV]-A-x-A-[LVF]-A. |
| Caspase family cysteine active site | K-P-K-[LIVMF]-[LIVMFY]-[LIVMF](2)-[QP]-[AF]-C-[RQG]-[GE]. |
| Caspase family histidine active site | H-x(2,4)-[SC]-x(2)-{A}-x-[LIVMF](2)-[ST]-H-G. |
| Catalase proximal active site signature | [IF]-x-[RH]-x(4)-[EQ]-R-x(2)-H-x(2)-[GAS]-[GASTFY]-[GAST]. |
| Catalase proximal heme-ligand signature | R-[LIVMFSTAN]-F-[GASTNP]-Y-x-D-[AST]-[QEH]. |
| Cathelicidins signature 1 | Y-x-[ED]-x-V-x-[RQ]-A-[LIVMA]-[DQG]-x-[LIVMFY]-N-[EQ]. |
| Cathelicidins signature 2 | F-x-[LIVM]-K-E-T-x-C-x(10)-C-x-F-[KR]-[KE]. |
| Caveolins signature | F-E-D-[LV]-I-A-[DE]-[PA]. |
| CBM1 (carbohydrate binding type-1) domain signature | C-G-G-x(4,7)-G-x(3)-C-x(4,5)-C-x(3,5)-[NHGS]-x-[FYWMI]-x(2)-Q-C. |
| CBM2a (carbohydrate-binding type-2) domain signature | W-N-[STAGR]-[STDN]-[LIVM]-x(2)-[GST]-x-[GST]-x(2)-[LIVMFT]-[GA]. |
| CDP-alcohol phosphatidyltransferases signature | D-G-x(2)-A-R-x(7,8)-G-x(3)-D-x(3)-D. |
| Cecropin family signature | W-x(0,2)-[KDN]-{Q}-{L}-K-[KRE]-[LI]-E-[RKN]. |
| Cell attachment sequence | R-G-D. |
| Cell cycle proteins ftsW / rodA / spoVE signature | [NV]-x(5)-[GTR]-[LIVMA]-x-P-[PTLIVME]-x-G-[LIVM]-x(3)-[LIVMFW](2)-S-[YSAQ]-G-G-[STN]-[SA]. |
| Cereal trypsin/alpha-amylase inhibitors family signature | C-x(4)-[SAGDV]-x(4)-[SPAL]-[LF]-x(2)-C-[RH]-x-[LIVMFYA](2)-x(3,4)-C. |
| Chalcone and stilbene synthases active site | R-[LIVMFYS]-x-[LIVM]-x-[QHG]-x-G-C-[FYNA]-[GAPV]-G-[GAC]-[STAVK]-x-[LIVMF]-[RAL]. |
| Channel forming colicins signature | T-x(2)-W-x-P-[LIVMFY](3)-x(2)-E. |
| Chaperonins clpA/B signature 1 | [DA]-[AI]-[SGA]-[NQS]-[LIVMF](2)-K-[PT]-x-[LM]-x(2)-G. |
| Chaperonins clpA/B signature 2 | [RGT]-[LIVMFY]-[DN]-x-[ST]-E-[LIVMFY]-x-[ED]-[KRQEAS]-x-[STA]-x-[STAD]-[KRS]-[LIVM]-x-G-[STAP]. |
| Chaperonins cpn10 signature | [LIVMFY]-x-P-[ILT]-x-[DEN]-[KR]-[LIVMFA](3)-[KREQS]-x(8,9)-[SG]-x-[LIVMFY](3). |
| Chaperonins cpn60 signature | A-[AS]-{L}-[DEQ]-E-{A}-{Q}-{R}-x-G-G-[GA]. |
| Chaperonins TCP-1 signature 1 | [RKEL]-[ST]-x-[LMFY]-G-P-x-[GSA]-x-x-K-[LIVMF](2). |
| Chaperonins TCP-1 signature 2 | [LIVM]-[TS]-[NK]-[DN]-[GA]-[AVNHK]-[TAVC]-[LIVM](2)-x(2)-[LIVMA]-x-[LIVM]-x-[SNH]-[PQHA]. |
| Chaperonins TCP-1 signature 3 | Q-[DEK]-x-x-[LIVMGTA]-[GA]-D-G-T. |
| Chitin recognition or binding domain signature | C-x(4,5)-C-C-S-x(2)-G-x-C-G-x(3,4)-[FYW]-C. |
| Chitin-binding type R&R domain signature | G-x(7)-[DEN]-G-x(6)-[FY]-x-A-[DNG]-x(2,3)-G-[FY]-x-[APV]. |
| Chitinases family 18 active site | [LIVMFY]-[DN]-G-[LIVMF]-[DN]-[LIVMF]-[DN]-x-E. |
| Chitinases family 19 signature 1 | C-x(4,5)-F-Y-[ST]-x(3)-[FY]-[LIVMF]-x-A-x(3)-[YF]-x(2)-F-[GSA]. |
| Chitinases family 19 signature 2 | [LIVM]-[GSA]-F-x-[STAG](2)-[LIVMFY]-W-[FY]-W-[LIVM]. |
| Chitosanases families 46 and 80 active sites signature | E-[DNQ]-x(8,17)-Y-x(7)-D-x-[RD]-[GP]-x-[TS]-x(3)-[AIVFLY]-G-x(5,11)-D. |
| Chloramphenicol acetyltransferase active site | Q-[LIV]-H-H-[SA]-x(2)-D-G-[FY]-H. |
| Chorismate synthase signature 1 | G-[DES]-S-H-[GC]-x(2)-[LIVM]-[GTIVLAMS]-x-[LIVTM]-[LIVM]-[DEST]-[GH]-x-[PV]. |
| Chorismate synthase signature 2 | [GE]-x(2)-S-[AG]-R-x-[ST]-x(3)-[VT]-x(2)-[GA]-[STAVY]-[LIVMF]. |
| Chorismate synthase signature 3 | R-[SHF]-D-[PSV]-[CSAVT]-x(4)-[SGAIVM]-x-[IVGSTAPM]-[LIVM]-x-E-[STAHNCG]-[LIVMA]. |
| Chromo domain signature | [FYL]-x-[LIVMC]-[KR]-W-x-[GDNR]-[FYWLME]-x(5,6)-[ST]-W-[ESV]-[PSTDEN]-x(2,3)-[LIVMC]. |
| Citrate synthase signature | G-[FYAV]-[GA]-H-x-[IV]-x(1,2)-[RKTQ]-x(2)-[DV]-[PS]-R. |
| Class A bacterial acid phosphatases signature | G-S-Y-P-S-G-H-T. |
| Clathrin adaptor complexes medium chain signature 1 | [IVT]-[GSP]-W-R-x(2,3)-[GAD]-x(2)-[HY]-x(2)-N-x-[LIVMAFY](3)-D-[LIVM]-[LIVMT]-E. |
| Clathrin adaptor complexes medium chain signature 2 | [LIV]-x-[FL]-[IQ]-P-P-x-G-x-[LIVMFY]-x-[LV]-x(2)-Y. |
| Clathrin adaptor complexes small chain signature | [LIVMC]-[LIVM]-Y-[KR]-x(4)-L-Y-F. |
| Clathrin light chain signature 1 | F-L-A-[QH]-[QE]-E-S. |
| Clathrin light chain signature 2 | [KR]-[DS]-x-[SE]-[KR]-[LIVMF]-[KR]-x-[LIVM]-[LIVMY]-[LIVM]-x-L-[KA]. |
| Claudin family signature | [GN]-L-W-x(2)-C-x(7,9)-[STDENQH]-C. |
| Clostridium cellulosome enzymes repeated domain signature | D-[LIVMFY]-[DNV]-x-[DNS]-x(2)-[LIVM]-[DN]-[SALM]-x-D-x(3)-[LIVMF]-x-[RKS]-x-[LIVMF]. |
| Clusterin signature 1 | C-K-P-C-L-K-x-T-C. |
| Clusterin signature 2 | C-L-[RK]-M-[RK]-x-[EQ]-C-[ED]-K-C. |
| CO II and nitrous oxide reductase dinuclear copper centers signature | V-x-H-x(33,40)-C-x(3)-C-x(3)-H-x(2)-M. |
| Coagulation factors 5/8 type C domain (FA58C) signature 1 | [GASP]-W-x(7,15)-[FYW]-[LIV]-x-[LIVFA]-[GSTDEN]-x(6)-[LIVF]-x(2)-[IV]-x-[LIVT]-[QKMT]-G. |
| Coagulation factors 5/8 type C domain (FA58C) signature 2 | P-x(8,10)-[LM]-R-x-[GE]-[LIVP]-x-G-C. |
| COE family signature | C-S-R-C-C-[DE]-[KR]-K-S-C. |
| Coenzyme A transferases signature 1 | [DN]-[GN]-x(2)-[LIVMFA](3)-G-G-F-x(3)-G-x-P. |
| Coenzyme A transferases signature 2 | [LF]-[HQ]-S-E-N-G-[LIVF](2)-[GA]. |
| Colipase signature | Y-x(2)-Y-Y-x-C-x-C. |
| Conantokin family signature | G-E-E-E-x(2)-[KE]-{E}(2)-x(0,1)-E-x-[ILA]-R-E. |
| Connexins signature 1 | C-[DNH]-[TL]-x-[QT]-P-G-C-x(2)-[VAIL]-C-[FY]-D. |
| Connexins signature 2 | C-x(3,4)-P-C-x(2,3)-[LIVMTA]-[DENT]-C-[FYN]-[LIVMQ]-[SA]-[KRH]-P. |
| Contryphan family signature | G(0,1)-C-[PV]-[WL]-x-P-[YW]-C-x(0,1)>. |
| Copper amine oxidase copper-binding site signature | T-x-[GS]-x(2)-H-[LIVMF]-x(3)-E-[DE]-x-P. |
| Copper amine oxidase topaquinone signature | [LIVM]-[LIVMA]-[LIVMF]-x(4)-[ST]-x(2)-N-Y-[DE]-[YN]. |
| Copper type II, ascorbate-dependent monooxygenases signature 1 | H-H-M-x(2)-F-x-C. |
| Copper type II, ascorbate-dependent monooxygenases signature 2 | H-x-F-x(4)-H-T-H-x(2)-G. |
| Copper-fist DNA-binding domain signature | M-[LIVMFP]-[LIVMF](2)-x(3)-[KN]-[MY]-A-C-x(2)-C-[IL]-[KR]-x-H-[KR]-x(3)-C-x-H-x(8,9)-[KR]-x-[KRP]-G-R-P. |
| Copper/Zinc superoxide dismutase signature 1 | [GA]-[IMFAT]-H-[LIVF]-H-{S}-x-[GP]-[SDG]-x-[STAGDE]. |
| Copper/Zinc superoxide dismutase signature 2 | G-[GNHD]-[SGA]-[GR]-x-R-x-[SGAWRV]-C-x(2)-[IV]. |
| Coproporphyrinogen III oxidase signature | K-x-[WQA]-[CA]-x(2)-[FYH](2)-x-[LIVM]-x-[HY]-R-x-E-x-R-G-[LIVMT]-G-G-[LIVM]-F-[FY]-D. |
| Cornichon family signature | [VI]-x(3)-[DE]-L-x(2)-D-[FY]-x-[NS]-[PS]-I-[DE]. |
| Corticotropin-releasing factor family signature | [PQA]-x-[LIVM]-S-[LIVM]-x(2)-[PST]-[LIVMF]-x-[LIVM]-L-R-x(2)-[LIVMW]. |
| CRISP family signature 1 | [GDER]-[HR]-[FYWH]-[TVS]-[QA]-[LIVM]-[LIVMA]-W-x(2)-[STN]. |
| CRISP family signature 2 | [LIVMFYH]-[LIVMFY]-x-C-[NQRHS]-Y-x-[PARH]-x-[GL]-N-[LIVMFYWDN]. |
| Crossover junction endodeoxyribonuclease ruvC signature | G-x-[GA]-x-[AG]-x-K-x-[EQA]-[IVM]-x(16,19)-D-x-[SAVT]-D-[AG]-x-[AGS]-[LIVMCA]-[ACS]. |
| Crp-type HTH domain signature | [LIVM]-[STAG]-[RHNWM]-x(2)-[LIM]-[GA]-x-[LIVMFYAS]-[LIVSC]-[GA]-x-[STACN]-x(2)-[MST]-x(1,2)-[GSTN]-R-x-[LIVMF]-x(2)-[LIVMF]. |
| CTF/NF-I DNA-binding domain signature | R-K-R-K-Y-F-K-K-H-E-K-R. |
| Cullin family signature | [LIV]-[KL]-x(2)-[LIVM]-x(2)-L-[IL]-[DEQGVT]-[KRHNQ]-x-[YT]-[LIVM]-x-R-x(5,7)-[FYLV]-x-Y-x-[SAT]. |
| Cutinase, aspartate and histidine active sites | C-x(3)-D-x-[IV]-C-x-G-[GST]-x(2)-[LIVM]-x(2,3)-H. |
| Cutinase, serine active site | P-x-[STA]-x-[LIV]-[IVT]-x-[GS]-G-Y-S-[QL]-G. |
| Cyclic nucleotide-binding domain signature 1 | [LIVM]-[VIC]-x-{H}-G-[DENQTA]-x-[GAC]-{L}-x-[LIVMFY](4)-x(2)-G. |
| Cyclic nucleotide-binding domain signature 2 | [LIVMF]-G-E-x-[GAS]-[LIVM]-x(5,11)-R-[STAQ]-A-x-[LIVMA]-x-[STACV]. |
